In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 22nd, 2008 | 37 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 0.89 | 4.47 | -71.34 | 4 | 12 | -1 | 184 | 517.511 | 15 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PTN1-1-E | Protein-tyrosine Phosphatase 1B (cluster #1 Of 4), Eukaryotic | Eukaryotes | 7943 | 0.19 | Binding ≤ 10μM |
PTN1-1-E | Protein-tyrosine Phosphatase 1B (cluster #1 Of 4), Eukaryotic | Eukaryotes | 9000 | 0.19 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
PTN1_HUMAN | P18031 | Protein-tyrosine Phosphatase 1B, Human | 9000 | 0.19 | Binding ≤ 10μM |
Description | Species |
---|---|
Growth hormone receptor signaling | |
Integrin alphaIIb beta3 signaling | |
Regulation of IFNA signaling | |
Regulation of IFNG signaling |