| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 22nd, 2008 | 19 | Yes |
Popular Name: DNC004852 DNC004852
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.95 | 8.25 | -36.52 | 1 | 3 | 1 | 21 | 256.373 | 2 | ↓ |
| Hi High (pH 8-9.5) | 2.95 | 5.97 | -6.69 | 0 | 3 | 0 | 19 | 255.365 | 2 | ↓ |
| Mid Mid (pH 6-8) | 2.95 | 6.23 | -25.49 | 1 | 3 | 1 | 21 | 256.373 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH3-1-E | Histamine H3 Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 7 | 0.60 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH3_HUMAN | Q9Y5N1 | Histamine H3 Receptor, Human | 6.8 | 0.60 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Histamine receptors |
