| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 32 | No |
Popular Name: DNC005784 DNC005784
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.90 | 12.07 | -46.21 | 2 | 6 | 1 | 59 | 431.56 | 6 | ↓ |
| Hi High (pH 8-9.5) | 4.90 | 9.87 | -13.49 | 1 | 6 | 0 | 58 | 430.552 | 6 | ↓ |
| Mid Mid (pH 6-8) | 4.90 | 10.17 | -30.96 | 2 | 6 | 1 | 59 | 431.56 | 6 | ↓ |
| Lo Low (pH 4.5-6) | 4.90 | 12.38 | -96.76 | 3 | 6 | 2 | 60 | 432.568 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MCHR1-2-E | Melanin-concentrating Hormone Receptor 1 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 16 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 16 | 0.34 | Binding ≤ 1μM |
| MCHR1_HUMAN | Q99705 | Melanin-concentrating Hormone Receptor 1, Human | 16 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| G alpha (q) signalling events | |
| Peptide ligand-binding receptors |
