Physical Representations
Type
pH range
|
xlogP
|
Des A‑Pol
Apolar desolvation
(kcal/mol)
|
Des Pol
Polar desolvation
(kcal/mol)
|
H Don
H-bond donors
|
H Acc
H-bond acceptors
|
Chg
Net charge
|
tPSA
(Ų)
|
MWT
Molecular weight
(g/mol)
|
RB
Rotatable bonds
|
DL |
Ref
Reference (pH 7)
|
0.35 |
5.55 |
-55.98 |
3 |
6 |
1 |
90 |
301.37 |
6 |
↓
|
Clustered Target Annotations
Code |
Organism Class |
Affinity (nM) |
LE (kcal/mol/atom) |
Type |
DPP2-2-E |
Dipeptidyl Peptidase II (cluster #2 Of 2), Eukaryotic |
Eukaryotes |
5718 |
0.33 |
Binding ≤ 10μM
|
DPP4-2-E |
Dipeptidyl Peptidase IV (cluster #2 Of 3), Eukaryotic |
Eukaryotes |
298 |
0.42 |
Binding ≤ 10μM
|
DPP8-1-E |
Dipeptidyl Peptidase VIII (cluster #1 Of 2), Eukaryotic |
Eukaryotes |
856 |
0.39 |
Binding ≤ 10μM
|
Reactome Annotations from Targets (via Uniprot)
Description |
Species |
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) |
|
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polyp |
|
No pre-computed analogs available. Try a structural similarity search.