Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	5.02	8.7	-43.59	2	2	1	25	337.27	0	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	5.02	8.27	-40.74	0	2	-1	26	335.254	0	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD1-1-E	Dopamine D1 Receptor (cluster #1 Of 4), Eukaryotic	Eukaryotes	3	0.54	Binding ≤ 10μM
DRD1-1-E	Dopamine D1 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	4	0.53	Functional ≤ 10μM
DRD2-1-E	Dopamine D2 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	38	0.47	Functional ≤ 10μM
DRD5-1-E	Dopamine D5 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	1	0.57	Functional ≤ 10μM
DRD2-2-E	Dopamine D2 Receptor (cluster #2 Of 24), Eukaryotic	Eukaryotes	88	0.45	Binding ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
DRD1_HUMAN	P21728	Dopamine D1 Receptor, Human	3.2	0.54	Binding ≤ 1μM
DRD2_HUMAN	P14416	Dopamine D2 Receptor, Human	88	0.45	Binding ≤ 1μM
DRD1_HUMAN	P21728	Dopamine D1 Receptor, Human	3.2	0.54	Binding ≤ 10μM
DRD2_HUMAN	P14416	Dopamine D2 Receptor, Human	88	0.45	Binding ≤ 10μM
DRD1_HUMAN	P21728	Dopamine D1 Receptor, Human	3.8	0.54	Functional ≤ 10μM
DRD2_HUMAN	P14416	Dopamine D2 Receptor, Human	37.5	0.47	Functional ≤ 10μM
DRD5_HUMAN	P21918	Dopamine D5 Receptor, Human	1.2	0.57	Functional ≤ 10μM