| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 23rd, 2008 | 35 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.27 | 7.4 | -58.65 | 6 | 7 | 1 | 113 | 475.613 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Binding ≤ 10μM |
| GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.36 | Functional ≤ 10μM |
| Z50597-1-O | Rattus Norvegicus (cluster #1 Of 12), Other | Other | 1 | 0.36 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 0.6 | 0.37 | Binding ≤ 1μM |
| GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 0.6 | 0.37 | Binding ≤ 10μM |
| GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 0.6 | 0.37 | Functional ≤ 10μM |
| Z50597 | Z50597 | Rattus Norvegicus | 0.6 | 0.37 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Peptide ligand-binding receptors |
