In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 23rd, 2008 | 17 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.68 | 4.31 | -4.18 | 0 | 3 | 0 | 22 | 235.327 | 4 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT1A-1-E | Serotonin 1a (5-HT1a) Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 1000 | 0.49 | Binding ≤ 10μM |
5HT1B-1-E | Serotonin 1b (5-HT1b) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.49 | Binding ≤ 10μM |
5HT1D-1-E | Serotonin 1d (5-HT1d) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.49 | Binding ≤ 10μM |
5HT1F-2-E | Serotonin 1f (5-HT1f) Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 1000 | 0.49 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT1A_RAT | P19327 | Serotonin 1a (5-HT1a) Receptor, Rat | 1000 | 0.49 | Binding ≤ 1μM |
5HT1B_RAT | P28564 | Serotonin 1b (5-HT1b) Receptor, Rat | 1000 | 0.49 | Binding ≤ 1μM |
5HT1D_RAT | P28565 | Serotonin 1d (5-HT1d) Receptor, Rat | 1000 | 0.49 | Binding ≤ 1μM |
5HT1F_RAT | P30940 | Serotonin 1f (5-HT1f) Receptor, Rat | 1000 | 0.49 | Binding ≤ 1μM |
5HT1A_RAT | P19327 | Serotonin 1a (5-HT1a) Receptor, Rat | 1000 | 0.49 | Binding ≤ 10μM |
5HT1B_RAT | P28564 | Serotonin 1b (5-HT1b) Receptor, Rat | 1000 | 0.49 | Binding ≤ 10μM |
5HT1D_RAT | P28565 | Serotonin 1d (5-HT1d) Receptor, Rat | 1000 | 0.49 | Binding ≤ 10μM |
5HT1F_RAT | P30940 | Serotonin 1f (5-HT1f) Receptor, Rat | 1000 | 0.49 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (i) signalling events | |
Serotonin receptors |