| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 25 | Yes |
Popular Name: Arachidonoyl2'-fluoroethylamide Arachidonoyl2'-fluoroethylamide
Find On: PubMed — Wikipedia — Google
CAS Number: 166100-37-4
N-(2-fluro-ethyl) arachidonoyl amine
N-(2-fluro-ethyl)-5Z,8Z,11Z,14Z-eicosatetraenoyl amine
N-(2-fluro-ethyl)arachidonoylamide; arachidonoyl-(2'-fluoroethyl)amide
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.58 | 13.52 | -9.7 | 1 | 2 | 0 | 29 | 349.534 | 16 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CNR1-3-E | Cannabinoid CB1 Receptor (cluster #3 Of 5), Eukaryotic | Eukaryotes | 9 | 0.45 | Binding ≤ 10μM |
| CNR2-2-E | Cannabinoid CB2 Receptor (cluster #2 Of 3), Eukaryotic | Eukaryotes | 908 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CNR1_RAT | P20272 | Cannabinoid CB1 Receptor, Rat | 26.7 | 0.42 | Binding ≤ 1μM |
| CNR2_MOUSE | P47936 | Cannabinoid CB2 Receptor, Mouse | 908 | 0.34 | Binding ≤ 1μM |
| CNR1_RAT | P20272 | Cannabinoid CB1 Receptor, Rat | 26.7 | 0.42 | Binding ≤ 10μM |
| CNR2_MOUSE | P47936 | Cannabinoid CB2 Receptor, Mouse | 908 | 0.34 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class A/1 (Rhodopsin-like receptors) | |
| G alpha (i) signalling events |
No pre-computed analogs available. Try a structural similarity search.