Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.98	10.9	-49.65	4	8	-1	133	422.509	11	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	2.98	10.63	-104.55	3	8	-2	135	421.501	11	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	2.98	11.22	-66.21	5	8	0	134	423.517	11	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
THAS-1-E	Thromboxane-A Synthase (cluster #1 Of 3), Eukaryotic	Eukaryotes	200	0.30	Binding ≤ 10μM
TA2R-1-E	Thromboxane A2 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	610	0.28	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
THAS_HUMAN	P24557	Thromboxane-A Synthase, Human	200	0.30	Binding ≤ 1μM
THAS_HUMAN	P24557	Thromboxane-A Synthase, Human	200	0.30	Binding ≤ 10μM
TA2R_HUMAN	P21731	Thromboxane A2 Receptor, Human	610	0.28	Functional ≤ 10μM

Description	Species
Eicosanoids	Homo sapiens (THAS_HUMAN)
G alpha (12/13) signalling events	Homo sapiens (TA2R_HUMAN)
G alpha (q) signalling events	Homo sapiens (TA2R_HUMAN)
Prostanoid ligand receptors	Homo sapiens (TA2R_HUMAN)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Homo sapiens (THAS_HUMAN)
Thromboxane signalling through TP receptor	Homo sapiens (TA2R_HUMAN)