Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	2.87	9.82	-93.49	1	7	0	112	432.5	9	↓ MOL2 SDF SMILES Flexibase
Hi High (pH 8-9.5)	4.74	7.7	-104.42	1	7	-2	121	431.492	8	↓ MOL2 SDF SMILES Flexibase
Mid Mid (pH 6-8)	2.87	9.78	-97.55	1	7	0	112	432.5	9	↓ MOL2 SDF SMILES Flexibase
Lo Low (pH 4.5-6)	4.74	7.24	-74.81	3	7	0	119	433.508	8	↓ MOL2 SDF SMILES Flexibase

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
THAS-1-E	Thromboxane-A Synthase (cluster #1 Of 3), Eukaryotic	Eukaryotes	230	0.29	Binding ≤ 10μM
TA2R-1-E	Thromboxane A2 Receptor (cluster #1 Of 1), Eukaryotic	Eukaryotes	830	0.27	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
THAS_HUMAN	P24557	Thromboxane-A Synthase, Human	230	0.29	Binding ≤ 1μM
THAS_HUMAN	P24557	Thromboxane-A Synthase, Human	230	0.29	Binding ≤ 10μM
TA2R_HUMAN	P21731	Thromboxane A2 Receptor, Human	830	0.27	Functional ≤ 10μM

Description	Species
Eicosanoids	Homo sapiens (THAS_HUMAN)
G alpha (12/13) signalling events	Homo sapiens (TA2R_HUMAN)
G alpha (q) signalling events	Homo sapiens (TA2R_HUMAN)
Prostanoid ligand receptors	Homo sapiens (TA2R_HUMAN)
Synthesis of Prostaglandins (PG) and Thromboxanes (TX)	Homo sapiens (THAS_HUMAN)
Thromboxane signalling through TP receptor	Homo sapiens (TA2R_HUMAN)