| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 25th, 2008 | 34 | Yes |
Popular Name: 5-[4-(4-dimethylaminophenyl)-4-hydroxy-1-piperidyl]-2,2-diphenyl-pentanenitrile 5-[4-(4-dimethylaminophenyl)-4-h…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.45 | 14.27 | -46.37 | 2 | 4 | 1 | 52 | 454.638 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1-1-E | C-C Chemokine Receptor Type 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1155 | 0.24 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 1155 | 0.24 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
