In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
June 26th, 2008 | 28 | Yes |
Popular Name: LS-141413 LS-141413
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.20 | 9.91 | -62.63 | 2 | 6 | 0 | 79 | 383.492 | 5 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT3A-1-E | Serotonin 3a (5-HT3a) Receptor (cluster #1 Of 5), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
5HT3B-1-E | Serotonin 3b (5-HT3b) Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
5HT3C-1-E | Serotonin 3c (5-HT3c) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
5HT3D-1-E | Serotonin 3d (5-HT3d) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
5HT3E-1-E | Serotonin 3e (5-HT3e) Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 0 | 0.00 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
5HT3A_HUMAN | P46098 | Serotonin 3a (5-HT3a) Receptor, Human | 0.48 | 0.47 | Binding ≤ 1μM |
5HT3A_RAT | P35563 | Serotonin 3a (5-HT3a) Receptor, Rat | 0.48 | 0.47 | Binding ≤ 1μM |
5HT3B_HUMAN | O95264 | Serotonin 3b (5-HT3b) Receptor, Human | 0.48 | 0.47 | Binding ≤ 1μM |
5HT3B_RAT | Q9JJ16 | Serotonin 3b (5-HT3b) Receptor, Rat | 0.48 | 0.47 | Binding ≤ 1μM |
5HT3C_HUMAN | Q8WXA8 | Serotonin 3c (5-HT3c) Receptor, Human | 0.48 | 0.47 | Binding ≤ 1μM |
5HT3D_HUMAN | Q70Z44 | Serotonin 3d (5-HT3d) Receptor, Human | 0.48 | 0.47 | Binding ≤ 1μM |
5HT3E_HUMAN | A5X5Y0 | Serotonin 3e (5-HT3e) Receptor, Human | 0.48 | 0.47 | Binding ≤ 1μM |
5HT3A_HUMAN | P46098 | Serotonin 3a (5-HT3a) Receptor, Human | 0.48 | 0.47 | Binding ≤ 10μM |
5HT3A_RAT | P35563 | Serotonin 3a (5-HT3a) Receptor, Rat | 0.48 | 0.47 | Binding ≤ 10μM |
5HT3B_RAT | Q9JJ16 | Serotonin 3b (5-HT3b) Receptor, Rat | 0.48 | 0.47 | Binding ≤ 10μM |
5HT3B_HUMAN | O95264 | Serotonin 3b (5-HT3b) Receptor, Human | 0.48 | 0.47 | Binding ≤ 10μM |
5HT3C_HUMAN | Q8WXA8 | Serotonin 3c (5-HT3c) Receptor, Human | 0.48 | 0.47 | Binding ≤ 10μM |
5HT3D_HUMAN | Q70Z44 | Serotonin 3d (5-HT3d) Receptor, Human | 0.48 | 0.47 | Binding ≤ 10μM |
5HT3E_HUMAN | A5X5Y0 | Serotonin 3e (5-HT3e) Receptor, Human | 0.48 | 0.47 | Binding ≤ 10μM |
Description | Species |
---|---|
Ligand-gated ion channel transport |