| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 26th, 2008 | 18 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.25 | 7.98 | -13.86 | 1 | 3 | 0 | 42 | 260.362 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CDK5-1-E | Cyclin-dependent Kinase 5 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 64 | 0.56 | Binding ≤ 10μM |
| Z104299-1-O | Cyclin-dependent Kinase 2/cyclin E1 (cluster #1 Of 1), Other | Other | 98 | 0.55 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Z104299 | Z104299 | Cyclin-dependent Kinase 2/cyclin E1 | 98 | 0.55 | Binding ≤ 1μM |
| CDK5_HUMAN | Q00535 | Cyclin-dependent Kinase 5, Human | 64 | 0.56 | Binding ≤ 1μM |
| Z104299 | Z104299 | Cyclin-dependent Kinase 2/cyclin E1 | 98 | 0.55 | Binding ≤ 10μM |
| CDK5_HUMAN | Q00535 | Cyclin-dependent Kinase 5, Human | 64 | 0.56 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| CRMPs in Sema3A signaling | |
| DARPP-32 events | |
| Factors involved in megakaryocyte development and platelet production |
