| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| June 27th, 2008 | 34 | Yes |
Popular Name: 2,7-dichloro-N-[1-[[(1E)-1-cyclooctenyl]methyl]-4-piperidyl]-9H-xanthene-9-carboxamide 2,7-dichloro-N-[1-[[(1E)-1-cyclo…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 7.35 | 14.99 | -42.71 | 2 | 4 | 1 | 43 | 500.49 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1-1-E | C-C Chemokine Receptor Type 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1900 | 0.24 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 240 | 0.27 | Binding ≤ 1μM |
| CCR1_MOUSE | P51675 | C-C Chemokine Receptor Type 1, Mouse | 1900 | 0.24 | Binding ≤ 10μM |
| CCR1_HUMAN | P32246 | C-C Chemokine Receptor Type 1, Human | 240 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
