UCSF

ZINC14294279

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Substance Information

In ZINC since Heavy atoms Benign functionality
July 6th, 2008 41 No

Popular Name: olmesartan medoxomil olmesartan medoxomil

Find On: PubMed — Wikipedia — Google

CAS Numbers: 144689-24-7 , 144689-63-4 , [144689-63-4]

Other Names:

(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylate

(5-methyl-2-oxo-1,3-dioxolen-4-yl)methoxy-4-(1-hydroxy-1-methylethyl)-2-propyl-1-(4-(2-(tetrazol-5-yl)phenyl)phenyl)methylimidazol-5-carboxylate

sartan

144689-63-4

144689-63-4; Benicar (TN); D01204; Olmesartan medoxomil (JAN/USAN); Olmetec (TN)

1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-, (5-methyl-2-oxo-1,3-dioxol-4-yl) methyl ester

1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl) (1,1'-biphenyl)-4-yl)methyl)-, (5-methyl-2-oxo-1,3-dioxol-4-yl) methyl ester; 1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-te

1H-Imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-, (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

1H-imidazole-5-carboxylic acid, 4-(1-hydroxy-1-methylethyl)-2-propyl-1-((2'-(1H-tetrazol-5-yl)(1,1'-biphenyl)-4-yl)methyl)-,(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl ester

AC-1601

AC1L2Y71

BAN

Benevas

Benicar

Benicar (TN)

BENICAR HCT; HYDROCHLOROTHIAZIDE; LS-187976; OLMESARTAN MEDOXOMIL

Benicar, Olmetec,Olmesartan

Benicar

Berlin-Chemie Brand of Olmesartan Medoxomil

Bio-0071

BRD-K78485176-001-02-9

BSPBio_003491

C097933

CHEMBL1200692

CID130881

Cs 866

CS-866

CS-866DM

CS-866RN

D01204

DAP001412

DB00275

DE-092

FDA

Forest Brand of Olmesartan Medoxomil

HMS1922L15

HMS2089K18

HMS2093K16

I06-0025

INN

KBio2_002490

KBio2_005058

KBio2_007626

KBio3_002711

KBioGR_001040

KBioSS_002498

KS-1182

L001061

LS-181818

MFCD00944911

MolPort-003-666-605

MolPort-005-935-047

NCGC00095136-01

NCGC00095136-02

Olmesartan

Olmesartan medoximil

Olmesartan Medoxomil

Olmesartan Medoxomil (BAN

Olmesartan Medoxomil (FDA

Olmesartan medoxomil (JAN/USAN)

Olmetec

Olmetec (TN)

Olvance

Openvas

S1587_Selleck

Sankyo Brand of Olmesartan Medoxomil

SPBio_000431

SPECTRUM1505205

Spectrum2_000506

Spectrum3_001676

Spectrum4_000740

Spectrum5_001556

Spectrum_001944

UNII-6M97XTV3HD

USAN)

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.28 13.68 -51.56 1 12 -1 160 557.587 11 ↓
Mid Mid (pH 6-8) 4.28 14.04 -61.07 2 12 0 162 558.595 11 ↓

Vendor Notes

Note Type Comments Provided By
Therapy Angiotensin II inhibitor prodrug, antihypertensive SMDC MicroSource
mechanism Angiotensin II receptor antagonists IBScreen Bioactives
Indications antiglaucoma, antihypertensive KeyOrganics Bioactives
biological_use Antihypertensive agent IBScreen Bioactives
mechanism Block the binding of angiotension II to the AT1 receptors in vascular muscle IBScreen Bioactives
PUBCHEM_PATENT_ID EP0344426B1; EP0558804B1; EP0574937A2; EP0574937B1; EP0600567B1; EP0630248A1; EP0630248B1; WO1993018774A1 IBM Patent Data
mechanism Prodrug-type angiotensin II receptor antagonist IBScreen Bioactives IBScreen Bioactives

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )