| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 18th, 2008 | 21 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.32 | 9.27 | -9.69 | 1 | 6 | 0 | 79 | 284.367 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CATL1-5-E | Cathepsin L (cluster #5 Of 5), Eukaryotic | Eukaryotes | 2530 | 0.37 | Binding ≤ 10μM |
| Q6R7Z5-1-E | Cathepsin B-like Cysteine Protease (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8300 | 0.34 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Q6R7Z5_9TRYP | Q6R7Z5 | Cathepsin B-like Cysteine Protease, 9tryp | 8300 | 0.34 | Binding ≤ 10μM |
| CATL1_HUMAN | P07711 | Cathepsin L, Human | 2530 | 0.37 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Assembly of collagen fibrils and other multimeric structures | |
| Collagen degradation | |
| Degradation of the extracellular matrix | |
| Endosomal/Vacuolar pathway | |
| MHC class II antigen presentation | |
| Trafficking and processing of endosomal TLR |
