| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 18th, 2008 | 30 | Yes |
Popular Name: 4-[(Z)-1-[4-(2-dimethylaminoethoxy)phenyl]-4-hydroxy-2-phenyl-but-1-enyl]phenol 4-[(Z)-1-[4-(2-dimethylaminoetho…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.35 | 9.65 | -39.72 | 3 | 4 | 1 | 54 | 404.53 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ERR3-1-E | Estrogen-related Receptor Gamma (cluster #1 Of 1), Eukaryotic | Eukaryotes | 250 | 0.31 | Binding ≤ 10μM |
| ESR1-1-E | Estrogen Receptor Alpha (cluster #1 Of 5), Eukaryotic | Eukaryotes | 250 | 0.31 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| ESR1_HUMAN | P03372 | Estrogen Receptor Alpha, Human | 250 | 0.31 | Binding ≤ 1μM |
| ERR3_HUMAN | P62508 | Estrogen-related Receptor Gamma, Human | 250 | 0.31 | Binding ≤ 1μM |
| ESR1_HUMAN | P03372 | Estrogen Receptor Alpha, Human | 250 | 0.31 | Binding ≤ 10μM |
| ERR3_HUMAN | P62508 | Estrogen-related Receptor Gamma, Human | 250 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Nuclear Receptor transcription pathway | |
| Nuclear signaling by ERBB4 |
