| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 23rd, 2004 | 12 | No |
Popular Name: 4-Hydrazinobenzenesulfonamide 4-Hydrazinobenzenesulfonamide
Find On: PubMed — Wikipedia — Google
CAS Numbers: 116714-46-6 , 17852-52-7 , 17965-82-1 , 27918-19-0 , 4392-54-5 , [17852-52-7] , [4392-54-5] , [6659-35-4]
4-(Aminosulfonyl)-phenylhydrazine hydrochloride
4-Aminosulfonylphenylhydrazine hydrochloride
4-Hydrazino-benzenesulfonamide hydrochloride
4-Hydrazinobenzene-1-sulfonamide HCl
4-hydrazinobenzene-1-sulfonamide hydrochloride
4-HydrazinobenzenesulfonaMide Hydrochloride
4-Hydrazinobenzenesulfonamide hydrochloride, 99%+
4-Hydrazinobenzenesulphonamide hydrochloride
4-Hydrazinylbenzenesulfonamide
4-hydrazinylbenzenesulfonamide hydrochloride
4-Sulfamicphenylhydrazine hydrochloride
4-Sulfonamide-phenylhydrazine hydrochloride
4-Sulfonamide-phenylhydrazinehydrochloride
4-Sulfonamidophenylhydrazine hydrochloride
4-Sulfonamidophenylhydrazine hydrochloride, 97%
4-Sulfonamidophenylhydrazine, HCl
Benzenesulfonamide, 4-hydrazino- (9CI)
benzenesulfonamide, 4-hydrazino-, monohydrochloride
HYDRAZINOBENZENESULFONAMIDE 4-
p-Sulfonamidophenyl hydrazine hydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -0.13 | -2.86 | -11.31 | 5 | 5 | 0 | 98 | 187.224 | 2 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| Mp [°C] | 180 | Acros Organics |
| MP | 195 - 197 | Enamine Building Blocks |
| MP | 195 - 205 | Enamine Building Blocks |
| MP | 195...197 | Enamine Building Blocks |
| Melting_Point | 217-219? dec. | Alfa-Aesar |
| Melting_Point | 217-219° dec. | Alfa-Aesar |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 95% | Fluorochem |
| Purity | 99% | Fluorochem |
| Warnings | IRRITANT | Matrix Scientific |
| S phrase | S24/25: Avoid contact with skin and eyes. | Acros Organics |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CAH-1-A | Carbonic Anhydrase (cluster #1 Of 2), Archaea | Archaea | 2200 | 0.66 | Binding ≤ 10μM |
| CYNT-1-B | Carbonic Anhydrase (cluster #1 Of 3), Bacterial | Bacteria | 334 | 0.76 | Binding ≤ 10μM |
| CAH1-5-E | Carbonic Anhydrase I (cluster #5 Of 12), Eukaryotic | Eukaryotes | 3900 | 0.63 | Binding ≤ 10μM |
| CAH12-1-E | Carbonic Anhydrase XII (cluster #1 Of 9), Eukaryotic | Eukaryotes | 11 | 0.93 | Binding ≤ 10μM |
| CAH14-1-E | Carbonic Anhydrase XIV (cluster #1 Of 8), Eukaryotic | Eukaryotes | 1450 | 0.68 | Binding ≤ 10μM |
| CAH15-2-E | Carbonic Anhydrase 15 (cluster #2 Of 6), Eukaryotic | Eukaryotes | 9540 | 0.59 | Binding ≤ 10μM |
| CAH2-6-E | Carbonic Anhydrase II (cluster #6 Of 15), Eukaryotic | Eukaryotes | 83 | 0.83 | Binding ≤ 10μM |
| CAH4-1-E | Carbonic Anhydrase IV (cluster #1 Of 16), Eukaryotic | Eukaryotes | 3215 | 0.64 | Binding ≤ 10μM |
| CAH5A-1-E | Carbonic Anhydrase VA (cluster #1 Of 10), Eukaryotic | Eukaryotes | 7700 | 0.60 | Binding ≤ 10μM |
| CAH5B-1-E | Carbonic Anhydrase VB (cluster #1 Of 9), Eukaryotic | Eukaryotes | 3500 | 0.64 | Binding ≤ 10μM |
| CAH6-7-E | Carbonic Anhydrase VI (cluster #7 Of 8), Eukaryotic | Eukaryotes | 1275 | 0.69 | Binding ≤ 10μM |
| CAH7-1-E | Carbonic Anhydrase VII (cluster #1 Of 8), Eukaryotic | Eukaryotes | 89 | 0.82 | Binding ≤ 10μM |
| CAH9-1-E | Carbonic Anhydrase IX (cluster #1 Of 11), Eukaryotic | Eukaryotes | 305 | 0.76 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CAH_METTE | P40881 | Carbonic Anhydrase, Mette | 220 | 0.78 | Binding ≤ 1μM |
| CYNT_HELPY | O24855 | Carbonic Anhydrase 1, Helpy | 316 | 0.76 | Binding ≤ 1μM |
| CAH2_HUMAN | P00918 | Carbonic Anhydrase II, Human | 300 | 0.76 | Binding ≤ 1μM |
| CAH9_HUMAN | Q16790 | Carbonic Anhydrase IX, Human | 265 | 0.77 | Binding ≤ 1μM |
| CAH7_HUMAN | P43166 | Carbonic Anhydrase VII, Human | 89 | 0.82 | Binding ≤ 1μM |
| CAH12_HUMAN | O43570 | Carbonic Anhydrase XII, Human | 11 | 0.93 | Binding ≤ 1μM |
| CAH_METTE | P40881 | Carbonic Anhydrase, Mette | 220 | 0.78 | Binding ≤ 10μM |
| CYNT_HELPY | O24855 | Carbonic Anhydrase 1, Helpy | 316 | 0.76 | Binding ≤ 10μM |
| CAH15_MOUSE | Q99N23 | Carbonic Anhydrase 15, Mouse | 9540 | 0.59 | Binding ≤ 10μM |
| CAH1_HUMAN | P00915 | Carbonic Anhydrase I, Human | 3900 | 0.63 | Binding ≤ 10μM |
| CAH2_HUMAN | P00918 | Carbonic Anhydrase II, Human | 300 | 0.76 | Binding ≤ 10μM |
| CAH4_HUMAN | P22748 | Carbonic Anhydrase IV, Human | 3200 | 0.64 | Binding ≤ 10μM |
| CAH4_BOVIN | Q95323 | Carbonic Anhydrase IV, Bovin | 3200 | 0.64 | Binding ≤ 10μM |
| CAH9_HUMAN | Q16790 | Carbonic Anhydrase IX, Human | 265 | 0.77 | Binding ≤ 10μM |
| CAH5A_HUMAN | P35218 | Carbonic Anhydrase VA, Human | 7700 | 0.60 | Binding ≤ 10μM |
| CAH5B_HUMAN | Q9Y2D0 | Carbonic Anhydrase VB, Human | 3500 | 0.64 | Binding ≤ 10μM |
| CAH6_HUMAN | P23280 | Carbonic Anhydrase VI, Human | 1275 | 0.69 | Binding ≤ 10μM |
| CAH7_HUMAN | P43166 | Carbonic Anhydrase VII, Human | 89 | 0.82 | Binding ≤ 10μM |
| CAH12_HUMAN | O43570 | Carbonic Anhydrase XII, Human | 11 | 0.93 | Binding ≤ 10μM |
| CAH14_HUMAN | Q9ULX7 | Carbonic Anhydrase XIV, Human | 1450 | 0.68 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Erythrocytes take up carbon dioxide and release oxygen | |
| Erythrocytes take up oxygen and release carbon dioxide | |
| Regulation of gene expression by Hypoxia-inducible Factor | |
| Reversible hydration of carbon dioxide |
