| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| September 27th, 2005 | 28 | Yes |
Popular Name: ANTALARMIN HYDROCHLORIDE ANTALARMIN HYDROCHLORIDE
Find On: PubMed — Wikipedia — Google
CAS Number: 220953-69-5
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.25 | 17.13 | -20.55 | 1 | 4 | 1 | 35 | 379.572 | 6 | ↓ |
| Mid Mid (pH 6-8) | 6.25 | 16.71 | -9.3 | 0 | 4 | 0 | 34 | 378.564 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CRFR1-1-E | Corticotropin Releasing Factor Receptor 1 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 3 | 0.43 | Binding ≤ 10μM |
| CRFR2-1-E | Corticotropin Releasing Factor Receptor 2 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.45 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CRFR1_RAT | P35353 | Corticotropin Releasing Factor Receptor 1, Rat | 1 | 0.45 | Binding ≤ 1μM |
| CRFR1_HUMAN | P34998 | Corticotropin Releasing Factor Receptor 1, Human | 0.84 | 0.45 | Binding ≤ 1μM |
| CRFR2_RAT | P47866 | Corticotropin Releasing Factor Receptor 2, Rat | 1 | 0.45 | Binding ≤ 1μM |
| CRFR1_HUMAN | P34998 | Corticotropin Releasing Factor Receptor 1, Human | 0.84 | 0.45 | Binding ≤ 10μM |
| CRFR1_RAT | P35353 | Corticotropin Releasing Factor Receptor 1, Rat | 1 | 0.45 | Binding ≤ 10μM |
| CRFR2_RAT | P47866 | Corticotropin Releasing Factor Receptor 2, Rat | 1 | 0.45 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class B/2 (Secretin family receptors) | |
| G alpha (s) signalling events |
