| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 6th, 2004 | 26 | Yes |
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CAS Number: 292143-94-3
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.80 | -2.66 | -29.41 | 2 | 5 | 0 | 71 | 390.892 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOL-4-V | Human Herpesvirus 6 DNA Polymerase (cluster #4 Of 4), Viral | Viruses | 460 | 0.34 | Binding ≤ 10μM |
| Z50530-1-O | Human Herpesvirus 5 (cluster #1 Of 5), Other | Other | 600 | 0.34 | Functional ≤ 10μM |
| Z80583-1-O | Vero (Kidney Cells) (cluster #1 Of 7), Other | Other | 3000 | 0.30 | Functional ≤ 10μM |
| Z80954-1-O | HFF (Foreskin Fibroblasts) (cluster #1 Of 4), Other | Other | 90 | 0.38 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| DPOL_VZVD | P09252 | DNA Polymerase, Vzvd | 460 | 0.34 | Binding ≤ 1μM |
| DPOL_HHV11 | P04293 | Human Herpesvirus 1 DNA Polymerase, Hhv11 | 500 | 0.34 | Binding ≤ 1μM |
| DPOL_HCMVA | P08546 | Human Herpesvirus 5 DNA Polymerase, Hcmva | 400 | 0.34 | Binding ≤ 1μM |
| DPOL_VZVD | P09252 | DNA Polymerase, Vzvd | 460 | 0.34 | Binding ≤ 10μM |
| DPOL_HHV11 | P04293 | Human Herpesvirus 1 DNA Polymerase, Hhv11 | 500 | 0.34 | Binding ≤ 10μM |
| DPOL_HCMVA | P08546 | Human Herpesvirus 5 DNA Polymerase, Hcmva | 400 | 0.34 | Binding ≤ 10μM |
| Z80954 | Z80954 | HFF (Foreskin Fibroblasts) | 600 | 0.34 | Functional ≤ 10μM |
| Z50530 | Z50530 | Human Herpesvirus 5 | 600 | 0.34 | Functional ≤ 10μM |
| Z80583 | Z80583 | Vero (Kidney Cells) | 3000 | 0.30 | Functional ≤ 10μM |
No pre-computed analogs available. Try a structural similarity search.