| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 7th, 2004 | 23 | No |
Popular Name: ZPCK ZPCK
Find On: PubMed — Wikipedia — Google
CAS Numbers: 26049-94-5 , 26049-94-5; 26049-98-9 , [26049-94-5]
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.91 | 9.5 | -13.52 | 1 | 4 | 0 | 55 | 331.799 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CMA1-1-E | Mast Cell Protease 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 400 | 0.39 | Binding ≤ 10μM |
| Z50425-3-O | Plasmodium Falciparum (cluster #3 Of 22), Other | Other | 10000 | 0.30 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CMA1_HUMAN | P23946 | Chymase, Human | 400 | 0.39 | Binding ≤ 1μM |
| CMA1_HUMAN | P23946 | Chymase, Human | 400 | 0.39 | Binding ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 10000 | 0.30 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Activation of Matrix Metalloproteinases | |
| Metabolism of Angiotensinogen to Angiotensins | |
| Signaling by SCF-KIT |
