In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
August 3rd, 2008 | 34 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 4.90 | 10.82 | -51.01 | 3 | 5 | 1 | 71 | 476.618 | 7 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
biological_use | Antiestrogen | IBScreen Bioactives IBScreen Bioactives |
biological_use | Prevents bone loss and reduces serum cholesterol in ovariectomized rats | IBScreen Bioactives |
mechanism | Selective estrogen receptor modulator (SERM) | IBScreen Bioactives |
biological_use | Used in the treatment of postmenopausal osteoporosis | IBScreen Bioactives |