UCSF

ZINC15919389

Substance Information

In ZINC since Heavy atoms Benign functionality
August 3rd, 2008 34 Yes

CAS Number: 82640-04-8

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 4.90 10.81 -51.07 3 5 1 71 476.618 7

Vendor Notes

Note Type Comments Provided By
biological_use Antiestrogen IBScreen Bioactives IBScreen Bioactives
biological_use Prevents bone loss and reduces serum cholesterol in ovariectomized rats IBScreen Bioactives
mechanism Selective estrogen receptor modulator (SERM) IBScreen Bioactives
biological_use Used in the treatment of postmenopausal osteoporosis IBScreen Bioactives

Activity (Go SEA)

Analogs ( Draw Identity 99% 90% 80% 70% )