In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
October 8th, 2004 | 11 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | -2.77 | -2.28 | -77.16 | 3 | 5 | -1 | 107 | 160.149 | 4 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
GRIK1-3-E | Glutamate Receptor Ionotropic Kainate 1 (cluster #3 Of 3), Eukaryotic | Eukaryotes | 82 | 0.90 | Binding ≤ 10μM |
GRIK2-2-E | Glutamate Receptor Ionotropic Kainate 2 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 82 | 0.90 | Binding ≤ 10μM |
GRIK3-2-E | Glutamate Receptor Ionotropic Kainate 3 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 82 | 0.90 | Binding ≤ 10μM |
GRIK4-2-E | Glutamate Receptor Ionotropic Kainate 4 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 82 | 0.90 | Binding ≤ 10μM |
GRIK5-2-E | Glutamate Receptor Ionotropic Kainate 5 (cluster #2 Of 2), Eukaryotic | Eukaryotes | 82 | 0.90 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
GRIK1_RAT | P22756 | Glutamate Receptor Ionotropic Kainate 1, Rat | 82 | 0.90 | Binding ≤ 1μM |
GRIK2_RAT | P42260 | Glutamate Receptor Ionotropic Kainate 2, Rat | 82 | 0.90 | Binding ≤ 1μM |
GRIK3_RAT | P42264 | Glutamate Receptor Ionotropic Kainate 3, Rat | 82 | 0.90 | Binding ≤ 1μM |
GRIK4_RAT | Q01812 | Glutamate Receptor Ionotropic Kainate 4, Rat | 82 | 0.90 | Binding ≤ 1μM |
GRIK5_RAT | Q63273 | Glutamate Receptor Ionotropic Kainate 5, Rat | 82 | 0.90 | Binding ≤ 1μM |
GRIK1_RAT | P22756 | Glutamate Receptor Ionotropic Kainate 1, Rat | 82 | 0.90 | Binding ≤ 10μM |
GRIK2_RAT | P42260 | Glutamate Receptor Ionotropic Kainate 2, Rat | 82 | 0.90 | Binding ≤ 10μM |
GRIK3_RAT | P42264 | Glutamate Receptor Ionotropic Kainate 3, Rat | 82 | 0.90 | Binding ≤ 10μM |
GRIK4_RAT | Q01812 | Glutamate Receptor Ionotropic Kainate 4, Rat | 82 | 0.90 | Binding ≤ 10μM |
GRIK5_RAT | Q63273 | Glutamate Receptor Ionotropic Kainate 5, Rat | 82 | 0.90 | Binding ≤ 10μM |
Description | Species |
---|---|
Activation of Ca-permeable Kainate Receptor | |
Activation of Na-permeable Kainate Receptors |