| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 9th, 2004 | 18 | Yes |
(6-Propoxy-benzothiazol-2-yl)-carbamic acid methyl ester
61570-90-9; D06158; Tiox (TN); Tioxidazole (USAN/INN)
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.11 | 4.9 | -10.62 | 1 | 5 | 0 | 60 | 266.322 | 5 | ↓ |
| Mid Mid (pH 6-8) | 2.74 | 2.91 | -45.31 | 0 | 5 | -1 | 67 | 265.314 | 5 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| biological_use | Anthelmintic | ZereneX Building Blocks |
| mechanism | Inhibitor of microtubule polymerisation . | ZereneX Building Blocks |
| biological_use | Anthelmintic | IBScreen Bioactives |
| mechanism | Causes degenerative alterations in the tegument and intestinal cells of the worm | IBScreen Bioactives |
| mechanism | Inhibitor of microtubule polymerisation. | IBScreen Bioactives |
No pre-computed analogs available. Try a structural similarity search.