| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| October 27th, 2008 | 16 | No |
Popular Name: Carbidopa Carbidopa
Find On: PubMed — Wikipedia — Google
CAS Numbers: 28860-95-9 , 302-53-4 , 38821-49-7 , 38821-49-7, 28860-95-9 [a , 38821-49-7, 28860-95-9 [anhydrous] , 57308-51-7 , [28860-95-9] , [38821-49-7]
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid
(-)-L-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazino-2-methylpropanoic acid
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid hydrate
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid monohydrate
(2S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid--water (1/1)
(alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid
(alphaS)-alpha-hydrazino-3,4-dihydroxy-alpha-methylbenzenepropanoic acid monohydrate
(S)-3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
(S)-alpha--Hydrazino-3,4-dihydroxy-alpha--methyl-benzenepropanoic acid monohydrate
3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
38821-49-7; CARBIDOPA; CPD001566944; SAM002703129
57308-51-7; C06870; Carbidopa-levodopa
alpha-Hydrazino-alpha-methyl-beta-(3,4-dihydroxyphenyl)propionic acid
Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, (S)-
Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate, (S)
Benzenepropanoic acid, alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate, (S)-
C10H14N2O4.C9H11NO4.H2O; CARBIDOPA AND LEVODOPA; CARBIDOPA; LEVODOPA; LS-178498; SINEMET; SINEMET CR
Carbidopa, Entacapone, & Levodopa
CARBIDOPA; CPD001566944; SAM002703129
CPD-11550; N-aminomethyldopa; alpha-methyldopahydrazine; carbidopa
Hydrocinnamic acid, (-)-L-alpha-hydrazino-3,4-dihydroxy-alpha-methyl-, monohydrate
HYDROCINNAMIC ACID, alpha-HYDRAZINO-3,4-DIHYDROXY-alpha-METHYL-, L-
KINSON, 3-(3,4-DIHYDROXY-PHENYL)-2-HYDRAZINO-2-METHYL-PROPIONIC ACID
L-3-(3,4-Dihydroxyphenyl)-2-methyl-2-hydrazinopropionic acid
L-alpha-(3,4-dihydroxybenzyl)-alpha-hydrazinopropionic acid monohydrate
L-alpha-Methyl-alpha-hydrazino-beta-(3,4-dihydroxyphenylpropionic acid
L-alpha-Methyl-beta-(3,4-dihydroxyphenyl)-alpha-hydrazinopropionic acid
S(-)-alpha-Hydrazino-3,4-dihydroxy-alpha-methylhydrocinnamic acid monohydrate
S-(-)-alpha-Hydrazino-3,4-dihydroxy-2-methylbenzenepropanoic acid
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | -2.81 | -0.86 | -41.32 | 6 | 6 | 0 | 123 | 226.232 | 4 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| ALOGPS_SOLUBILITY | 3.73e+00 g/l | DrugBank-approved |
| Purity | 97% | Fluorochem |
| Purity | 98+% | Matrix Scientific |
| Purity | >99% | Matrix Scientific |
| biological_use | Antiparkinsonian agent | IBScreen Bioactives IBScreen Bioactives |
| Indications | antiparkinsons | KeyOrganics Bioactives |
| Purity | BP2000 | APIChem |
| Target | Decarboxylase | Selleck Chemicals |
| Therapy | decarboxylase inhibitor, antiparkinsonism | SMDC MicroSource |
| mechanism | Dopa-decarboxylase inhibitor | IBScreen Bioactives |
| Warnings | IRRITANT | Matrix Scientific |
| PUBCHEM_SUBSTANCE_COMMENT | NCC_SAMPLE_SUPPLIER : LightBiologicals; NCC_SUPPLIER_STRUCTURE_ID : MZ-3023; NCC_SUPPLIER_SAMPLE_COMMENTS : WHITE POWDER; 1 water | NIH Clinical Collection via PubChem |
| Therapy | Peripherally active L-aromatic amino acid decarboxylase inhibitor; used in combination with levodopa for the treatment o | SMDC Iconix |
| PUBCHEM_SUBSTANCE_COMMENT | SAMPLE_SUPPLIER: LightBiologicals; SUPPLIER_STRUCTURE_ID: MZ-3023; SALT: 1 water; SUPPLIER_COMMENTS: WHITE POWDER | NIH Clinical Collection via PubChem |
| biological_use | Used in treatment of parkinsonism | IBScreen Bioactives |
No pre-computed analogs available. Try a structural similarity search.