| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 12th, 2008 | 27 | Yes |
Popular Name: (+)-Bicuculline (+)-Bicuculline
Find On: PubMed — Wikipedia — Google
CAS Numbers: 485-49-4 , [485-49-4]
485-49-4; Bicuculline (+); Prestwick_96
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.88 | 5.78 | -13.2 | 0 | 7 | 0 | 66 | 367.357 | 1 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| PUBCHEM_PATENT_ID | EP0002978A2; EP0046379A1; EP0046711A1; EP0050563A1; EP0073161A1; EP0082369A1; EP0089322A1; EP0092458A2; EP0092459A2; EP0094886A1; EP0105821A1; EP0114770A2; EP0118564A1; EP0118565A1; EP0118566A1; EP0124091A2; EP0130644A1; EP0134461A1; EP0135406A1; EP015827 | IBM Patent Data |
| Therapy | GABA antagonist | SMDC MicroSource |
| Target | GABA Receptor | Selleck Chemicals |
| mechanism | GABA(A)-receptor antagonist | IBScreen Bioactives |
| therap | GABAa antagonist | MicroSource Spectrum |
| UniProt Database Links | GBR1_CAEEL; GLRA1_DANRE | ChEBI |
| biological_use | Mimics epilepsy. | IBScreen Bioactives |
| Target | Stromal cell-derived factor 1(P48061)&C-X-C chemokine receptor type 4(P61073)&Caspase-3(P42574)&Gamma-aminobutyric acid type B receptor subunit 1(Q9UBS5)&Aldose reductase(P15121)&Estrogen receptor(P03372)&Cytochrome P450 1A1(P04798)&RAC-alpha serine/threo | Herbal Ingredients Targets |
| biological_use | Utilised in the in vitro study of epilepsy. | IBScreen Bioactives |
