| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 13th, 2008 | 20 | Yes |
Popular Name: (1R)-1-(3-methoxyphenyl)-N-[(4-methoxyphenyl)methyl]ethanamine (1R)-1-(3-methoxyphenyl)-N-[(4-m…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.54 | 7.64 | -45.72 | 2 | 3 | 1 | 35 | 272.368 | 6 | ↓ |
| Hi High (pH 8-9.5) | 3.54 | 6.39 | -6.42 | 1 | 3 | 0 | 30 | 271.36 | 6 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR-1-E | Calcium Sensing Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 370 | 0.45 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR_HUMAN | P41180 | Calcium Sensing Receptor, Human | 370 | 0.45 | Binding ≤ 1μM |
| CASR_HUMAN | P41180 | Calcium Sensing Receptor, Human | 370 | 0.45 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events | |
| G alpha (q) signalling events |
