In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
December 29th, 2008 | 27 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 3.52 | 8.5 | -10.45 | 1 | 6 | 0 | 69 | 366.465 | 6 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
HCAR2-1-E | HM74 Nicotinic Acid GPCR (cluster #1 Of 4), Eukaryotic | Eukaryotes | 3400 | 0.28 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
HCAR2_HUMAN | Q8TDS4 | Nicotinic Acid Receptor 1, Human | 3200 | 0.28 | Binding ≤ 10μM |
Description | Species |
---|---|
Class A/1 (Rhodopsin-like receptors) | |
G alpha (i) signalling events | |
Hydroxycarboxylic acid-binding receptors |