| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 4th, 2009 | 27 | No |
Popular Name: N-[(1S)-1-[4-(9H-fluoren-2-yloxy)phenyl]ethyl]-N-hydroxy-acetamide N-[(1S)-1-[4-(9H-fluoren-2-yloxy…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.97 | 10.82 | -14.04 | 1 | 4 | 0 | 50 | 359.425 | 4 | ↓ |
| Hi High (pH 8-9.5) | 4.97 | 11.68 | -43.03 | 0 | 4 | -1 | 53 | 358.417 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LOX5-1-E | Arachidonate 5-lipoxygenase (cluster #1 Of 6), Eukaryotic | Eukaryotes | 4900 | 0.28 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LOX5_RAT | P12527 | Arachidonate 5-lipoxygenase, Rat | 4900 | 0.28 | Binding ≤ 10μM |
