| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 4th, 2009 | 29 | Yes |
Popular Name: (R)-Butaprost (R)-Butaprost
Find On: PubMed — Wikipedia — Google
CAS Number: 69648-38-0
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.67 | 9.01 | -11.38 | 2 | 5 | 0 | 84 | 408.579 | 14 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R2-2-E | Prostanoid EP2 Receptor (cluster #2 Of 2), Eukaryotic | Eukaryotes | 2400 | 0.27 | Binding ≤ 10μM |
| PE2R2-1-E | Prostanoid EP2 Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 33 | 0.36 | Functional ≤ 10μM |
| PI2R-1-E | Prostanoid IP Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 37 | 0.36 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 2400 | 0.27 | Binding ≤ 10μM |
| PE2R2_MOUSE | Q62053 | Prostanoid EP2 Receptor, Mouse | 33 | 0.36 | Functional ≤ 10μM |
| PI2R_HUMAN | P43119 | Prostanoid IP Receptor, Human | 37 | 0.36 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Prostacyclin signalling through prostacyclin receptor | |
| Prostanoid ligand receptors |
