| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 7th, 2009 | 31 | Yes |
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.36 | 10.19 | -63.59 | 2 | 5 | -1 | 89 | 440.585 | 8 | ↓ |
| Lo Low (pH 4.5-6) | 5.36 | 9.07 | -23.47 | 3 | 5 | 0 | 87 | 441.593 | 8 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PD2R-1-E | Prostanoid DP Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 2 | 0.39 | Binding ≤ 10μM |
| PD2R-1-E | Prostanoid DP Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1 | 0.41 | Functional ≤ 10μM |
| Z50587-5-O | Homo Sapiens (cluster #5 Of 9), Other | Other | 1 | 0.41 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| PD2R_HUMAN | Q13258 | Prostanoid DP Receptor, Human | 1.9 | 0.39 | Binding ≤ 1μM |
| PD2R_HUMAN | Q13258 | Prostanoid DP Receptor, Human | 1.9 | 0.39 | Binding ≤ 10μM |
| Z50587 | Z50587 | Homo Sapiens | 0.9 | 0.41 | Functional ≤ 10μM |
| PD2R_HUMAN | Q13258 | Prostanoid DP Receptor, Human | 0.9 | 0.41 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Prostanoid ligand receptors |
