| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 9th, 2009 | 33 | No |
Popular Name: N,N-diisopropyl-4-[5-(4-methanehydrazonoylphenoxy)pentoxy]-3-methoxy-benzamide N,N-diisopropyl-4-[5-(4-methaneh…
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.85 | 10.54 | -17.61 | 2 | 7 | 0 | 86 | 455.599 | 13 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LT4R1-1-E | Leukotriene B4 Receptor 1 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.38 | Binding ≤ 10μM |
| LT4R2-1-E | Leukotriene B4 Receptor 2 (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.38 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| LT4R1_HUMAN | Q15722 | Leukotriene B4 Receptor 1, Human | 1 | 0.38 | Binding ≤ 1μM |
| LT4R2_HUMAN | Q9NPC1 | Leukotriene B4 Receptor 2, Human | 1 | 0.38 | Binding ≤ 1μM |
| LT4R1_HUMAN | Q15722 | Leukotriene B4 Receptor 1, Human | 1 | 0.38 | Binding ≤ 10μM |
| LT4R2_HUMAN | Q9NPC1 | Leukotriene B4 Receptor 2, Human | 1 | 0.38 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Leukotriene receptors |
