| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 12th, 2009 | 23 | Yes |
Popular Name: ent-CalindolHydrochloride ent-CalindolHydrochloride
Find On: PubMed — Wikipedia — Google
CAS Number: 728930-30-1
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.08 | 11.06 | -51.91 | 3 | 2 | 1 | 32 | 301.413 | 4 | ↓ |
| Hi High (pH 8-9.5) | 5.08 | 9.78 | -7.53 | 2 | 2 | 0 | 28 | 300.405 | 4 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR-1-E | Calcium Sensing Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.37 | Functional ≤ 10μM |
| CASR-1-E | Calcium Sensing Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1300 | 0.36 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CASR_RAT | P48442 | Calcium Sensing Receptor, Rat | 1000 | 0.37 | Functional ≤ 10μM |
| CASR_HUMAN | P41180 | Calcium Sensing Receptor, Human | 310 | 0.40 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events | |
| G alpha (q) signalling events |
