| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 14th, 2009 | 19 | Yes |
Popular Name: Methanone, (7-amino-1H-benzimidazol-2-yl)(4-methyl-1-piperazinyl)- Methanone, (7-amino-1H-benzimida…
Find On: PubMed — Wikipedia — Google
CAS Number: 673487-10-0
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.30 | 1.38 | -7.26 | 3 | 6 | 0 | 78 | 259.313 | 1 | ↓ |
| Mid Mid (pH 6-8) | 0.30 | 3.75 | -42.02 | 4 | 6 | 1 | 79 | 260.321 | 1 | ↓ |
| Mid Mid (pH 6-8) | 0.30 | 3.74 | -41.05 | 4 | 6 | 1 | 79 | 260.321 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH4-1-E | Histamine H4 Receptor (cluster #1 Of 4), Eukaryotic | Eukaryotes | 244 | 0.49 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| HRH4_HUMAN | Q9H3N8 | Histamine H4 Receptor, Human | 244 | 0.49 | Binding ≤ 1μM |
| HRH4_HUMAN | Q9H3N8 | Histamine H4 Receptor, Human | 244 | 0.49 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (i) signalling events | |
| Histamine receptors |
