| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 18th, 2009 | 27 | No |
Popular Name: N-Arachidonylmaleimide N-Arachidonylmaleimide
Find On: PubMed — Wikipedia — Google
CAS Numbers: 176977-56-3 , 876305-42-9
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 6.64 | 15.22 | -8.41 | 0 | 3 | 0 | 39 | 369.549 | 15 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| FAAH1-6-E | Anandamide Amidohydrolase (cluster #6 Of 7), Eukaryotic | Eukaryotes | 2180 | 0.29 | Binding ≤ 10μM |
| MGLL-5-E | Monoglyceride Lipase (cluster #5 Of 7), Eukaryotic | Eukaryotes | 140 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MGLL_HUMAN | Q99685 | Monoglyceride Lipase, Human | 140 | 0.36 | Binding ≤ 1μM |
| FAAH1_HUMAN | O00519 | Anandamide Amidohydrolase, Human | 2180 | 0.29 | Binding ≤ 10μM |
| MGLL_HUMAN | Q99685 | Monoglyceride Lipase, Human | 1120 | 0.31 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Acyl chain remodeling of DAG and TAG | |
| Arachidonate production from DAG | |
| Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
No pre-computed analogs available. Try a structural similarity search.