In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
February 23rd, 2009 | 17 | Yes |
Popular Name: [(1S,2S,3S,4R)-3-(3-methoxyphenyl)norbornan-2-yl]methanamine [(1S,2S,3S,4R)-3-(3-methoxypheny…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 2.86 | 5.55 | -46.4 | 3 | 2 | 1 | 37 | 232.347 | 3 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
SC6A3-1-E | Dopamine Transporter (cluster #1 Of 3), Eukaryotic | Eukaryotes | 8820 | 0.42 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
SC6A3_RAT | P23977 | Dopamine Transporter, Rat | 2010 | 0.47 | Binding ≤ 10μM |
Description | Species |
---|---|
Dopamine clearance from the synaptic cleft | |
Na+/Cl- dependent neurotransmitter transporters |