| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 24th, 2009 | 27 | Yes |
Popular Name: 3-(2,6-dichlorophenyl)-N-[4-(ethyl-methyl-amino)phenyl]-5-methyl-isoxazole-4-carboxamide 3-(2,6-dichlorophenyl)-N-[4-(eth…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.87 | 10.33 | -11.87 | 1 | 5 | 0 | 58 | 404.297 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5500 | 0.27 | Binding ≤ 10μM |
| GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4700 | 0.28 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 5500 | 0.27 | Binding ≤ 10μM |
| GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 4700 | 0.28 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Peptide ligand-binding receptors |
