In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
February 24th, 2009 | 33 | Yes |
Popular Name: [4-[4-[(3,4-dichlorophenyl)methyl]-1-piperidyl]-1-piperidyl]-(3-quinolyl)methanone [4-[4-[(3,4-dichlorophenyl)methy…
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.17 | 14.6 | -53.44 | 1 | 4 | 1 | 38 | 483.463 | 4 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CCR3-1-E | C-C Chemokine Receptor Type 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 458 | 0.27 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 458 | 0.27 | Binding ≤ 1μM |
CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 458 | 0.27 | Binding ≤ 10μM |
Description | Species |
---|---|
Chemokine receptors bind chemokines | |
G alpha (i) signalling events |