In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
February 28th, 2009 | 33 | Yes |
None
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.59 | 12.42 | -56.91 | 2 | 5 | 1 | 46 | 491.483 | 7 | ↓ |
Hi High (pH 8-9.5) | 5.59 | 12.54 | -49.05 | 2 | 5 | 1 | 46 | 491.483 | 7 | ↓ |
Lo Low (pH 4.5-6) | 5.59 | 14.66 | -131.5 | 3 | 5 | 2 | 47 | 492.491 | 7 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CCR3-1-E | C-C Chemokine Receptor Type 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 92 | 0.30 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 92 | 0.30 | Binding ≤ 1μM |
CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 92 | 0.30 | Binding ≤ 10μM |
Description | Species |
---|---|
Chemokine receptors bind chemokines | |
G alpha (i) signalling events |