| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 1st, 2009 | 33 | Yes |
Popular Name: N,N-dimethyl-4-[(1S)-1-(4-phenylpiperazin-1-yl)-2-[2-(p-tolyl)ethylamino]ethyl]aniline N,N-dimethyl-4-[(1S)-1-(4-phenyl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.30 | 13.22 | -48.12 | 2 | 4 | 1 | 26 | 443.659 | 9 | ↓ |
| Mid Mid (pH 6-8) | 5.30 | 15.15 | -136.24 | 3 | 4 | 2 | 28 | 444.667 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR3-1-E | C-C Chemokine Receptor Type 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 435 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 435 | 0.27 | Binding ≤ 1μM |
| CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 435 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
