| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 1st, 2009 | 32 | Yes |
Popular Name: (2R)-2-(4-methoxyphenyl)-2-(4-phenylpiperazin-1-yl)-N-[2-(p-tolyl)ethyl]ethanamine (2R)-2-(4-methoxyphenyl)-2-(4-ph…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 5.26 | 12.16 | -50.98 | 2 | 4 | 1 | 32 | 430.616 | 9 | ↓ |
| Mid Mid (pH 6-8) | 5.26 | 13.98 | -142.62 | 3 | 4 | 2 | 34 | 431.624 | 9 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR3-1-E | C-C Chemokine Receptor Type 3 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 597 | 0.27 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 597 | 0.27 | Binding ≤ 1μM |
| CCR3_HUMAN | P51677 | C-C Chemokine Receptor Type 3, Human | 597 | 0.27 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
