| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 1st, 2009 | 35 | Yes |
Popular Name: 1-[(2R,4R,5R)-4-fluoro-5-(trityloxymethyl)tetrahydrofuran-2-yl]pyrimidine-2,4-dione 1-[(2R,4R,5R)-4-fluoro-5-(trityl…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.26 | 10.76 | -13.87 | 1 | 6 | 0 | 73 | 472.516 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Q8II92-1-E | DUTP Pyrophosphatase (cluster #1 Of 1), Eukaryotic | Eukaryotes | 5000 | 0.21 | Binding ≤ 10μM |
| Z50425-16-O | Plasmodium Falciparum (cluster #16 Of 22), Other | Other | 2000 | 0.23 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| Q8II92_PLAF7 | Q8II92 | DUTP Pyrophosphatase, Plaf7 | 5000 | 0.21 | Binding ≤ 10μM |
| Z50425 | Z50425 | Plasmodium Falciparum | 2000 | 0.23 | Functional ≤ 10μM |
