In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
March 1st, 2009 | 42 | No |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 6.14 | 16.49 | -68.48 | 3 | 7 | 1 | 83 | 596.236 | 12 | ↓ |
Mid Mid (pH 6-8) | 6.14 | 14.32 | -20.76 | 2 | 7 | 0 | 82 | 595.228 | 12 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MC4R-1-E | Melanocortin Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 1000 | 0.20 | Binding ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
MC4R_HUMAN | P32245 | Melanocortin Receptor 4, Human | 1000 | 0.20 | Binding ≤ 1μM |
MC4R_HUMAN | P32245 | Melanocortin Receptor 4, Human | 1000 | 0.20 | Binding ≤ 10μM |
Description | Species |
---|---|
G alpha (s) signalling events | |
Peptide ligand-binding receptors |