| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 7th, 2009 | 34 | Yes |
Popular Name: 6-amino-2-butyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]quinazolin-4-one 6-amino-2-butyl-3-[[4-[2-(2H-tet…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.60 | 11.37 | -50 | 2 | 8 | -1 | 114 | 450.526 | 7 | ↓ |
| Lo Low (pH 4.5-6) | 4.60 | 11.47 | -17.09 | 3 | 8 | 0 | 115 | 451.534 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AGTR1-1-E | Type-1 Angiotensin II Receptor (cluster #1 Of 2), Eukaryotic | Eukaryotes | 1 | 0.37 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| AGTR1_HUMAN | P30556 | Angiotensin II Type 1 Receptor, Human | 1.3 | 0.37 | Binding ≤ 1μM |
| AGTR1_RABIT | P34976 | Angiotensin II Type 1a (AT-1a) Receptor, Rabit | 1.3 | 0.37 | Binding ≤ 1μM |
| AGTR1_HUMAN | P30556 | Angiotensin II Type 1 Receptor, Human | 1.3 | 0.37 | Binding ≤ 10μM |
| AGTR1_RABIT | P34976 | Angiotensin II Type 1a (AT-1a) Receptor, Rabit | 1.3 | 0.37 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (q) signalling events | |
| Peptide ligand-binding receptors |
