| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 7th, 2009 | 29 | Yes |
Popular Name: N-(4-aminocyclohexyl)-N-benzyl-4-(1H-indol-3-yl)butanamide N-(4-aminocyclohexyl)-N-benzyl-4…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.60 | 11.2 | -65.08 | 4 | 4 | 1 | 64 | 390.551 | 7 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MC4R-1-E | Melanocortin Receptor 4 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 8400 | 0.25 | Binding ≤ 10μM |
| MSHR-1-E | Melanocortin Receptor 1 (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4300 | 0.26 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| MSHR_MOUSE | Q01727 | Melanocortin Receptor 1, Mouse | 4300 | 0.26 | Binding ≤ 10μM |
| MC4R_HUMAN | P32245 | Melanocortin Receptor 4, Human | 8400 | 0.25 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Peptide ligand-binding receptors |
