| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 8th, 2009 | 19 | Yes |
Popular Name: DNC007926 DNC007926
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.58 | 3.43 | -12.23 | 3 | 5 | 0 | 85 | 253.261 | 2 | ↓ |
| Mid Mid (pH 6-8) | 2.58 | 4.19 | -41.8 | 2 | 5 | -1 | 88 | 252.253 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CXCR2-1-E | Interleukin-8 Receptor B (cluster #1 Of 2), Eukaryotic | Eukaryotes | 276 | 0.48 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CXCR2_HUMAN | P25025 | Interleukin-8 Receptor B, Human | 276 | 0.48 | Binding ≤ 1μM |
| CXCR2_HUMAN | P25025 | Interleukin-8 Receptor B, Human | 276 | 0.48 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Chemokine receptors bind chemokines | |
| G alpha (i) signalling events |
