| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| March 9th, 2009 | 21 | Yes |
Popular Name: GLP-1R agonist DMB GLP-1R agonist DMB
Find On: PubMed — Wikipedia — Google
CAS Number: 281209-71-0
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.76 | 4.39 | -11.9 | 1 | 5 | 0 | 72 | 348.255 | 3 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLP1R-1-E | Glucagon-like Peptide Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 32 | 0.50 | Binding ≤ 10μM |
| GLP1R-1-E | Glucagon-like Peptide Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 155 | 0.45 | Functional ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GLP1R_HUMAN | P43220 | Glucagon-like Peptide Receptor, Human | 32 | 0.50 | Binding ≤ 1μM |
| GLP1R_HUMAN | P43220 | Glucagon-like Peptide Receptor, Human | 32 | 0.50 | Binding ≤ 10μM |
| GLP1R_HUMAN | P43220 | Glucagon-like Peptide Receptor, Human | 101 | 0.47 | Functional ≤ 10μM |
| Description | Species |
|---|---|
| G alpha (s) signalling events | |
| Glucagon-like Peptide-1 (GLP1) regulates insulin secretion | |
| Glucagon-type ligand receptors |
No pre-computed analogs available. Try a structural similarity search.