In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
March 15th, 2009 | 37 | Yes |
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | -0.07 | 2.65 | -53.75 | 5 | 10 | 1 | 144 | 531.655 | 9 | ↓ |
Mid Mid (pH 6-8) | -0.07 | 2.34 | -25.73 | 4 | 10 | 0 | 142 | 530.647 | 9 | ↓ |
Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 209 | 0.25 | Binding ≤ 10μM |
GHSR-1-E | Ghrelin Receptor (cluster #1 Of 1), Eukaryotic | Eukaryotes | 69 | 0.27 | Functional ≤ 10μM |
Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
---|---|---|---|---|---|
GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 209 | 0.25 | Binding ≤ 1μM |
GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 209 | 0.25 | Binding ≤ 10μM |
GHSR_HUMAN | Q92847 | Ghrelin Receptor, Human | 69.2 | 0.27 | Functional ≤ 10μM |
Description | Species |
---|---|
G alpha (q) signalling events | |
Peptide ligand-binding receptors |