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Quick Search ZINC ID or SMILES

Synonyms (12)
Vendors (2)
Annotations (16)
Representations (1)
Notes (5)
Targets (3)
Clustered (3)
Reactome (3)
Rings (0)
Analogs (0)

ZINC30320665

30320665

Draw Identity 99% 90% 80% 70%

Substance Information

In ZINC since	Heavy atoms	Benign functionality
March 27^th, 2009	36	No

Popular Name: UDP-D-glucose UDP-D-glucose

Find On: PubMed — Wikipedia — Google

CAS Numbers: 133-89-1 , 28053-08-9 , [117756-22-6]

Other Names:

(UDP)glucose; (UPD)-glucose; UDP glucose; UDP-a-D-Glucose; UDP-alpha-D-Glucose; UDP-alpha-delta-Glucose; UDP-D-glucose; UDP-delta-glucose; UDP-Glc; UDP-Glucose; UDPG; UDPglucose; Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester; Uri

133-89-1; C00029; UDP-D-glucose; UDP-alpha-D-glucose; UDP-glucose; UDPglucose; Uridine diphosphate glucose

28053-08-9; Bivitox (TN); Cogalactoisomerase sodium salt; D07738; Toxepasi (TN); Uridine 5'-diphosphoglucose disodium

CHEBI:27234; CHEBI:28532; CHEBI:13498; CHEBI:13505; CHEBI:9895; CHEBI:9845; CHEBI:22103

CPD-12575; UDP-alpha-D-glucose

UDP-alpha-D-glucose

UDP-D-glucose(2-)

UDP-D-glucose; UDP-D-glucose dianion; UDP-Glc(2-)

UDP-Glc; Uridine 5'-(trihydrogen diphosphate), P'-alpha-D-glucopyranosyl ester; Uridine 5'-(trihydrogen diphosphate), mono-alpha-d-glucopyranosyl ester; uridinediphosphoglucose

Uridine 5'-diphosphoglucose disodium salt

[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl {[(3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl phosphonato]oxy}phosphonate

SMILES:

Download: MOL2 SDF SMILES Flexibase

Annotations

Vendors

Physical Representations

Type pH range	xlogP	Des A‑Pol Apolar desolvation (kcal/mol)	Des Pol Polar desolvation (kcal/mol)	H Don H-bond donors	H Acc H-bond acceptors	Chg Net charge	tPSA (Å²)	MWT Molecular weight (g/mol)	RB Rotatable bonds	DL
Ref Reference (pH 7)	-5.03	-14.08	-161	7	19	-2	303	564.286	9	↓ MOL2 SDF SMILES Flexibase

Vendor Notes

Note Type	Comments	Provided By
UniProt Database Links	5GT1_PERFR; 5GT2_PERFR; 5GT_GENTR; 5GT_VERHY; 5NTD_LUTLO; 5NTD_RHIMP; AA5GT_DIACA; ACEA_GLUXY; ACSA1_GLUHA; ACSA1_GLUXY; ACSA2_GLUHA; AGLF_HALVD; AGLM_HALVD; AGS1_SCHPO; ALG5_DICDI; ALG5_DROME; ALG5_HUMAN; ALG5_MOUSE; ALG5_SCHPO; ALG5_YEAST; AMGDS_ACHLA	ChEBI
UniProt Database Links	AGLF_HALVD; ALG5_DICDI; ALG5_DROME; ALG5_HUMAN; ALG5_MOUSE; ALG5_SCHPO; ALG5_YEAST; AOG_PHAAN; ARAE1_ARATH; CEGTA_XENLA; CEGTB_XENLA; CEGT_HUMAN; CEGT_MOUSE; CEGT_RAT; CEGT_XENTR; CELA_GLUXY; CGT1_CAEEL; CGT2_CAEEL; CGT3_CAEEL; CGT_FRAAN; CRTX_ESCVU; CRTX	ChEBI
PUBCHEM_PATENT_ID	EP0359347A2; EP0359347B1; EP0380470B1; EP0414171A2; EP0414171B1; EP0471687B1; EP0497878B1; EP0576592A1; EP0576592B1; EP0635063A1; EP0635063B1; EP0642526A1; EP0642526B1; EP0671917A1; EP0728841A3; EP0748868A2; EP0771878A1; EP0816489A1; EP0850244A1; EP085851	IBM Patent Data
Reactome Database Links	REACT_115635; REACT_118657; REACT_120743; REACT_1315; REACT_15538; REACT_169102; REACT_169150; REACT_169159; REACT_169223; REACT_169252; REACT_169306; REACT_169355; REACT_169387; REACT_169406; REACT_18318; REACT_2047; REACT_22143; REACT_22239; REACT_22287	ChEBI
Patent Database Links	US2003170653	ChEBI

Activity (Go SEA)

Clustered Target Annotations
Code	Description	Organism Class	Affinity (nM)	LE (kcal/mol/atom)	Type
P2RY2-1-E	Purinergic Receptor P2Y2 (cluster #1 Of 1), Eukaryotic	Eukaryotes	10000	0.19	Functional ≤ 10μM
P2RY6-1-E	Pyrimidinergic Receptor P2Y6 (cluster #1 Of 1), Eukaryotic	Eukaryotes	1600	0.23	Functional ≤ 10μM
P2Y14-1-E	P2Y Purinoceptor 14 (cluster #1 Of 2), Eukaryotic	Eukaryotes	400	0.25	Functional ≤ 10μM

ChEMBL Target Annotations
Uniprot	Swissprot	Description	Affinity (nM)	LE (kcal/mol/atom)	Type
P2Y14_HUMAN	Q15391	Purinergic Receptor P2Y14, Human	261	0.26	Functional ≤ 10μM
P2RY2_HUMAN	P41231	Purinergic Receptor P2Y2, Human	10000	0.19	Functional ≤ 10μM
P2RY6_HUMAN	Q15077	Pyrimidinergic Receptor P2Y6, Human	1600	0.23	Functional ≤ 10μM

Direct Reactome Annotations (via ChEBI)

Description	Species
Collagen biosynthesis and modifying enzymes	Mus musculus Caenorhabditis elegans Drosophila melanogaster Homo sapiens Rattus norvegicus Xenopus tropicalis Canis familiaris Bos taurus Danio rerio
Formation of the active cofactor, UDP-glucuronate	Caenorhabditis elegans Saccharomyces cerevisiae Xenopus tropicalis Canis familiaris Mus musculus Arabidopsis thaliana Sus scrofa Oryza sativa Bos taurus Homo sapiens Gallus gallus Rattus norvegicus Schizosaccharomyces pombe Dictyostelium discoideum Drosophila melanogaster Taeniopygia guttata Danio rerio
G alpha (i) signalling events	Xenopus tropicalis Bos taurus Sus scrofa Gallus gallus Rattus norvegicus Taeniopygia guttata Canis familiaris Mus musculus Danio rerio Homo sapiens
Galactose catabolism	Homo sapiens Schizosaccharomyces pombe Drosophila melanogaster Taeniopygia guttata Gallus gallus Danio rerio Dictyostelium discoideum Rattus norvegicus Canis familiaris Saccharomyces cerevisiae Caenorhabditis elegans Sus scrofa Xenopus tropicalis Arabidopsis thaliana Bos taurus Oryza sativa Mus musculus
Glycogen synthesis	Drosophila melanogaster Rattus norvegicus Xenopus tropicalis Taeniopygia guttata Caenorhabditis elegans Danio rerio Dictyostelium discoideum Saccharomyces cerevisiae Bos taurus Canis familiaris Arabidopsis thaliana Mus musculus Sus scrofa Schizosaccharomyces pombe Homo sapiens Oryza sativa Gallus gallus
Glycosphingolipid metabolism	Canis familiaris Bos taurus Mus musculus Caenorhabditis elegans Rattus norvegicus Sus scrofa Taeniopygia guttata Gallus gallus Homo sapiens Drosophila melanogaster Xenopus tropicalis Danio rerio
HS-GAG biosynthesis	Danio rerio Rattus norvegicus Oryza sativa Drosophila melanogaster Homo sapiens Bos taurus Arabidopsis thaliana Mus musculus Caenorhabditis elegans Sus scrofa Dictyostelium discoideum Taeniopygia guttata Canis familiaris
Keratan sulfate biosynthesis	Taeniopygia guttata Arabidopsis thaliana Canis familiaris Sus scrofa Bos taurus Mus musculus Homo sapiens Drosophila melanogaster Rattus norvegicus Caenorhabditis elegans Danio rerio Dictyostelium discoideum Oryza sativa
P2Y receptors	Sus scrofa Homo sapiens Bos taurus Gallus gallus Xenopus tropicalis Mus musculus Taeniopygia guttata Danio rerio Canis familiaris
Pre-NOTCH Processing in the Endoplasmic Reticulum	Sus scrofa Bos taurus Danio rerio Gallus gallus Taeniopygia guttata Homo sapiens Canis familiaris Rattus norvegicus Mus musculus Drosophila melanogaster
Synthesis of dolichyl-phosphate-glucose	Gallus gallus Homo sapiens Sus scrofa Rattus norvegicus Arabidopsis thaliana Caenorhabditis elegans Canis familiaris Xenopus tropicalis Drosophila melanogaster Schizosaccharomyces pombe Danio rerio Bos taurus Dictyostelium discoideum Taeniopygia guttata Mus musculus Saccharomyces cerevisiae Oryza sativa
Transport of nucleotide sugars	Mus musculus Bos taurus Taeniopygia guttata Canis familiaris Sus scrofa Arabidopsis thaliana Drosophila melanogaster Caenorhabditis elegans Dictyostelium discoideum Danio rerio Rattus norvegicus Oryza sativa Homo sapiens
Trehalose biosynthesis	Mycobacterium tuberculosis

Reactome Annotations from Targets (via Uniprot)

Description	Species
G alpha (i) signalling events	Homo sapiens (P2Y14_HUMAN)
G alpha (q) signalling events	Homo sapiens (P2RY2_HUMAN)
P2Y receptors	Homo sapiens (P2RY2_HUMAN)

Analogs ( Draw Identity 99% 90% 80% 70% )

No pre-computed analogs available. Try a structural similarity search.

Synonyms (12)
Vendors (2)
Annotations (16)
Representations (1)
Notes (5)
Targets (3)
Clustered (3)
Reactome (3)
Rings (0)
Analogs (0)